师资队伍

副教授

闫瑾

日期: 2021-03-10   浏览:

姓 名:

闫瑾

性 别:

出生年月:

1992.01

职 务:


职 称:

副教授

评聘时间:

2024.07

所在系:

环境科学

专业:

环境科学

主要研究方向:

环境污染物毒理效应,环境污染与健康

主讲课程:

环境毒理学、生态学基础

联系电话:


电子邮箱:

yanjin@usts.edu.cn

个人简介:

近年来一直从事环境污染物的毒理学研究,基于多种体内外模型探究环境污染的毒性效应和毒理机制以及环境污染与健康的关系。目前已在国内外学术期刊上发表SCI论文30余篇,第一作者发表SCI论文8篇。主持国家自然科学基金青年项目1项,江苏省高校自然科学研究面上项目1项。

学习经历:

2021. 1—至今 苏州科技大学 环境科学与工程学院 环境科学系

2018.11—2020.1 德国卡尔斯鲁厄理工学院(KIT)博士联合培养

2014.9—2020.7 中国农业大学 博士 硕博连读

2010.9—2014.7 中国农业大学 学士

个人荣誉:

苏州科技大学优秀研究生导师团队

社会兼职:

EE&H期刊青年编委,江苏省环境诱变剂学会委员

论文论著:

1.Yan J., Fang L., Ni A., Xi M., Li J., Zhou X., Qian Q., Wang Z., Wang X., & Wang, H. Long-Term Neurotoxic Effects and Alzheimer’s Disease Risk of Early EHDPP Exposure in Zebrafish: Insights from Molecular Mechanisms to Adult Pathology (2024).Environmental Science and Technology, 58, 19152−19162

2. Yan J.,;Takamiya M.,Ding Z.,Pace, G.,Rastegar S.,Schoch S.,Koberle B.,Hartwig A., Dickmeis T,.& Weiss C. Zebrafish as a model organism in One Health Toxicology: Impact of solvents and exposure routes on the toxicity of platinum anticancer drugs,Environment International, 2025, 197: 109349

3. Yan, J., Zhao, Z., Xia, M., Chen, S., Wan, X., He, A., Sheng G., Wang X., Qian Q., & Wang, H. (2022). Induction of lipid metabolism dysfunction, oxidative stress and inflammation response by tris (1-chloro-2-propyl) phosphate in larval/adult zebrafish. Environment International, 160, 107081.

4. Ni, A.,Fang, L., Xi, M., Li, J., Qian, Q., Wang, Z., Wang, X., Wang, H., &Yan, J. (2024). Neurotoxic effects of 2-ethylhexyl diphenyl phosphate exposure on zebrafish larvae: Insight into inflammation-driven changes in early motor behavior.Science of The Total Environment, 915, 170131.

5.Yan, J., Fang, L., Zhao, Z., Su, X., Xi, M., Huang, Y., Li J., Chang R., Zhang W., Qian Q., Wang, Z., & Wang, H. (2024). Adolescent exposure to tris (1, 3-dichloro-2-propyl) phosphate (TCPP) induces reproductive toxicity in zebrafish through hypothalamic-pituitary-gonadal axis disruption.Science of The Total Environment, 953, 176096.

6.Li, J., Fang, L., Xi, M., Ni, A., Qian, Q., Wang, Z., Wang, H., &Yan, J. (2024). Toxic effects of triclosan on hepatic and intestinal lipid accumulation in zebrafish via regulation of m6A-RNA methylation.Aquatic Toxicology, 269, 106884.

7. Wan, X., Wang, H., Qian, Q., &Yan, J. (2023). MiR-133b as a crucial regulator of TCS-induced cardiotoxicity via activating β-adrenergic receptor signaling pathway in zebrafish embryos.Environmental Pollution, 334, 122199.

8.Yan, J., Li, J., Wang, Y., Song, J., Ni, A., Fang, L., Xi, M., Qian, Q., Wang, Z., & Wang, H. (2024). Deciphering the molecular mediators of triclosan-induced lipid accumulation: Intervention via short-chain fatty acids and miR-101a.Environmental Pollution, 343, 123153.

9.Yan, J., Zhao, Z., Xia, M., Chen, S., Wan, X., He, A., Wang, X. & Wang, H. (2022). Induction of lipid metabolism dysfunction, oxidative stress and inflammation response by tris (1-chloro-2-propyl) phosphate in larval/adult zebrafish. Environment international, 160, 107081.

10. Yan, J., Wang, D., Miao, J., Liu, C., Wang, Y., Teng, M., Zhou, Z. & Zhu, W. (2021).Effects of incremental endosulfan sulfate exposure and high fat diet on lipid metabolism, glucose homeostasis and gut microbiota in mice.Environmental pollution. 268

11. Yan, J., Xiang, B., Wang, D., Tang, S., Teng, M., Yan, S., Zhou, Z.& Zhu, W. (2019).Different Toxic Effects of Racemate, Enantiomers, and Metabolite of Malathion on HepG2 Cells Using High-Performance Liquid Chromatography–Quadrupole–Time-of-Flight-Based Metabolomics. Journal of agricultural and food chemistry, 67(7), 1784-1794.

12. Yan, J.,Zhu, W., Wang, D., Teng, M., Yan, S., & Zhou, Z. (2019).Different effects ofα-endosulfan,β-endosulfan, and endosulfan sulfate on sex hormone levels, metabolic profile and oxidative stress in adult mice testes.Environmental research, 169, 315-325.

13. Yan, J.,Wang, D., Miao, J., Liu, C., Wang, Y., Teng, M., Zhou, Z & Zhu, W. (2018).Discrepant effects ofα-endosulfan,β-endosulfan, and endosulfan sulfate on oxidative stress and energy metabolism in the livers and kidneys of mice.Chemosphere, 205, 223-233.

14. Yan, J.,Zhang, R., Wang, X., Wang, Y., Wang, D., Zhou, Z., & Zhu, W. (2016).Enantiomeric Separation of Chiral Pesticides by Permethylatedβ‐Cyclodextrin Stationary Phase in Reversed Phase Liquid Chromatography.Chirality, 28(5), 409-414.

15. Yan, J.,Zhang, P., Wang, X., Xu, M., Wang, Y., Zhou, Z., & Zhu, W. (2016).Stereoselective Degradation of alpha‐Cypermethrin and Its Enantiomers in Rat Liver Microsomes. Chirality, 28(1), 58-64.

16. Yan, J.,Zhang, P., Wang, X., Wang, Y., Zhou, Z., & Zhu, W. (2014).Stereoselective degradation of chiral fungicide myclobutanil in rat liver microsomes. Chirality, 26(1), 51-55.

专利:


承担项目:

国家自然科学基金-青年基金 30万,2022.1 - 2024.12,主持

江苏省高校自然科学研究面上项目,3万,2021.10 - 2023.9 主持

浙江省农科院技术服务,4.8万,2025.10-2027.10 主持

获奖成果:

  1. 第十届大学生生命科学竞赛二等奖(国赛)

  2. 第二届全国大学生生态环境管理科研创新大赛二等奖

  3. 苏州市环境科学学会优秀论文一等奖

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